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Premium performance and cGMP compliance with single-use flowmeter Proline Promass U 500
Premium performance and cGMP compliance with single-use flowmeter Proline Promass U 500
Specs at a glance
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Max. measurement error
Mass flow (liquid): ±0.5%
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Measuring range
0 to 75 kg/h (0 to 165,3 lb/min)
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Medium temperature range
3 to 60°C (37.4 to 140°F)
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Max. process pressure
6 bar (87 psi)
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Wetted materials
Measuring tubes: Stainless steel 1.4435, 316L
Hose connection nipple: Makrolon Rx 1805 polycarbonate
Field of application
Promass U 500 is the ideal single-use flowmeter for biopharmaceutical applications in the life sciences industry. It represents the response to the shift from multi-use to single-use devices and from batch to continuous manufacturing. Offering multivariable measurement, Promass U 500 provides enhanced reliability, high accuracy, and industry compliance according to cGMP. The flowmeter is especially suited for up- and downstream applications in the monoclonal antibodies (mAb) process.
The sensor comprises a disposable part, available in four line sizes, and a permanently installed base unit, fitting all line sizes. Heartbeat Technology automatically recognizes the flow range and verifies the validity of the factory calibration after installation. This simplifies commissioning and eliminates the need for calibration in the field. Equipped with built-in web server, WLAN, and up to 4 I/Os, the transmitter provides easy operation and additional process and device information.
Benefits
Best-in-class measuring accuracy – Coriolis technology with multivariable measurement
Highest turndown ratio – one sensor fits all line sizes of disposable
cGMP compliance – designed according to the latest standards and guidelines, equipped with required attributes and documentation
Simple, fast commissioning – one-hand mounting and automated calibration data transfer
Self drainability or air bubble escape – thanks to different mounting angles
No field calibration needed – automated verification with integrated Heartbeat Technology
Digital integration – modern single pair Ethernet based communication protocols
Videos
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The Coriolis flow measuring principle
Xpert selection
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable

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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
FLEX selections | Technical excellence | Simplicity |
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Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
Variable |
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Measuring principle
Coriolis
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Product headline
Single-use specialist for Biotech applications, with a remote version with up to 4 I/Os.
Modern fieldbus communication protocols (2-wire).
Highest measurement performance for liquids in single-use processes for the Life Sciences Industry. -
Sensor features
One sensor fits all DN – single variant with 4 disposable line sizes provides highest turndown ratio . One-hand mounting of disposable – easy
commissioning due to intuitive clamping mechanism. Mounting angle - self drainabillity or air bubble escape.
Disposable made of 1.4435 (316L) and polycarbonate. Fully traceable cGMP compliance. One sensor fits four line sizes: ¹⁄₈ to 1". -
Transmitter features
Full access to process and diagnostic information –
numerous, freely combinable I/Os and Ethernet. Reduced complexity and variety – freely configurable I/O functionality. Integrated verification – Heartbeat Technology.
Remote version with up to 4 I/Os. Backlit display with touch control and WLAN access. Standard cable between sensor and transmitter. -
Nominal diameter range
¹⁄₈" to 1"
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Wetted materials
Measuring tubes: Stainless steel 1.4435, 316L
Hose connection nipple: Makrolon Rx 1805 polycarbonate -
Measured variables
Mass, density, temperature
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Max. measurement error
Mass flow (liquid): ±0.5%
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Measuring range
0 to 75 kg/h (0 to 165,3 lb/min)
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Max. process pressure
6 bar (87 psi)
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Medium temperature range
3 to 60°C (37.4 to 140°F)
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Ambient temperature range
5 to 40°C (41 to 104°F)
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Transmitter housing material
Aluminum, AlSi10Mg, coated
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Degree of protection
Transmitter: IP66/67, Type 4X enclosure
Sensor: IP54 -
Display/Operation
4-line backlit display with touch control (operation from outside)
Configuration via local display and operating tools possible -
Outputs
"4 outputs:
4-20 mA HART (active/passive)
4-20 mA WirelessHART
4-20 mA (active/passive)
Pulse/frequency/switch output (active/passive)
Double pulse output (active/passive)
Relay output" -
Inputs
Status input
4-20 mA input -
Digital communication
Modbus RS485, PROFINET over Ethernet-APL
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Power supply
AC 100 to 230 V / DC 24 V (non-hazardous area)
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Product safety
CE, C-tick, EAC marking
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Functional safety
Functional safety according to IEC 61508, applicable in safety-relevant applications in accordance with IEC 61511
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Hygienic approvals and certificates
cGMP compliance, ASME BPE, BPOG, FDA
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