50 years of ISFET - Unbreakable pH sensors
The journey of ion-selective field-effect transistors (ISFETs) as biochemical and biological sensors

In brief
- ISFET technology is based on an MOS transistor arrangement.
- ISFET pH sensors address the critical needs of the food and life sciences industries.
- Modern ISFET sensors provide good CIP stability.
ISFET evolution
The first big milestone was the publication by P. Bergveld in 1970 which described how ion activities in electrochemical or biological systems could be measured by combining the principles of MOS transistors and glass electrodes.
In the following years ISFET technology evolved in many directions, one of which was pH measurement. The reason was clear: to create an unbreakable, glass-free
Endnotes
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