Developed according to industry standards for single-use sensors, this Raman optic system is cGMP qualified and gamma sterilizable. The system is comprised of two parts - a reusable optic and a disposable fitting for single-use bioreactors (SUB). The Raman optic system for single use in conjunction with the Rxn-10 probe offers the same quality data as reusable Raman probes. This ability allows customers to develop products and processes without limitations of the final production reactor type.
Raman downstream process measurement of biosimilars - Alvotech’s testing of the protein purification process during ultrafiltration/diafiltration (UF/DF)
KBI Biopharma is monitoring a diverse array of cell lines and cell concentrations in minimal volume for automated cell cultivation in the Life Sciences industry.
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Raman application guide for the life science industry -
Trusted composition analysis for the life sciences
English version - 04/2022
New version available in English
A guide to our Raman spectroscopy application notes for the
Life Science industry (featuring the Raman Rxn2 analyzer,
Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe,
Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single
use optic system / SUB, immersion optic, non-contact optic).
Accessory optics for the Rxn-10 probe
Technical Information
Technical Information (TI)
English version - 05/2023
New version available in English
System design and specifications for Rxn-10 probe optics: Raman immersion optics (KIO1), non-contact optics (KNCO1), bIO-Optics (KLBIO1), bio multi optics (KRBMO), bio sleeves (KRBSL), and Raman optic system for single use (KRSU1)
Accessory optics for the Rxn-10 probe
Operating Instructions
Operating Instruction (BA)
English version - 05/2023
New version available in English
Commissioning, operation, and maintenance details for Rxn-10 probe optics: Raman immersion optics (KIO1), non-contact optics (KNCO1), bIO-Optics (KLBIO1), bio multi optics (KRBMO), bio sleeves (KRBSL) and Raman optic system for single use (KRSU1)
Accessory optics for the Rxn-10 probe
Brief Operating Instructions
Short Instruction (KA)
English version - 05/2023
New version available in English
Quickstart guide for Rxn-10 probe optics: Raman immersion optics (KIO1), non-contact optics (KNCO1), bIO-Optics (KLBIO1), bio multi optics (KRBMO), bio sleeves (KRBSL), and Raman optic system for single use (KRSU1)
Graphic illustrating the core elements of Biopharma 4.0 including product lifecycle stages, role of PAT/QbD, and 12 key advanced technologies for scientists and process engineers in the Life Sciences, applicable to Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use, and Raman calibration & verification kits).
Endress+Hauser - your one-source Life Sciences technology partner
PU (Publication)
English version - 06/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Raman application guide for the life science industry -
Trusted composition analysis for the life sciences
PU (Publication)
English version - 04/2022
New version available in English
A guide to our Raman spectroscopy application notes for the Life Science industry (featuring the Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe, Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single use optic system / SUB, immersion optic, non-contact optic).
